MMRN2 Back

multimerin 2

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NCBI Description of MMRN2

This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


MMRN2 is highly significantly mutated in
MMRN2 is significantly mutated in
MMRN2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for MMRN2