MMRN1 Back

multimerin 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of MMRN1

Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin.

Community Annotation of MMRN1 Add / Edit MMRN1: Annotations

No community annotations yet for MMRN1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


MMRN1 is highly significantly mutated in
MMRN1 is significantly mutated in
MMRN1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for MMRN1