MMP28 Back

matrix metallopeptidase 28

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NCBI Description of MMP28
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Transcript variants encoding different isoforms have been described.

Community Annotation of MMP28 Add / Edit MMP28: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MMP28 is highly significantly mutated in
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MMP28 is significantly mutated in
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MMP28 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MMP28