MMP27 Back

matrix metallopeptidase 27

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NCBI Description of MMP27

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.

Community Annotation of MMP27 Add / Edit MMP27: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MMP27 is highly significantly mutated in
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MMP27 is significantly mutated in
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MMP27 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for MMP27