MMP23B Back

matrix metallopeptidase 23B

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NCBI Description of MMP23B
This gene (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region.

Community Annotation of MMP23B Add / Edit MMP23B: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MMP23B is highly significantly mutated in
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MMP23B is significantly mutated in
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MMP23B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MMP23B