MMP21 Back

matrix metallopeptidase 21

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NCBI Description of MMP21

This gene encodes a member of the matrix metalloproteinase family. Proteins in this family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction, and tissue remodeling,and disease processes, such as asthma and metastasis. The encoded protein may play an important role in embryogenesis, particularly in neuronal cells, as well as in lymphocyte development and survival.

Community Annotation of MMP21 Add / Edit MMP21: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


MMP21 is highly significantly mutated in
MMP21 is significantly mutated in
MMP21 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for MMP21