MMEL1 Back

membrane metallo-endopeptidase-like 1

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NCBI Description of MMEL1
The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart.

Community Annotation of MMEL1 Add / Edit MMEL1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MMEL1 is highly significantly mutated in
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MMEL1 is significantly mutated in
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MMEL1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MMEL1