MMD Back

monocyte to macrophage differentiation-associated

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NCBI Description of MMD

This protein is expressed by in vitro differentiated macrophages but not freshly isolated monocytes. Although sequence analysis identifies seven potential transmembrane domains, this protein has little homology to G-protein receptors and it has not been positively identified as a receptor. A suggested alternative function is that of an ion channel protein in maturing macrophages.

Community Annotation of MMD Add / Edit MMD: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MMD is highly significantly mutated in
(none)
MMD is significantly mutated in
(none)
MMD is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for MMD