MLL5 Back

myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)

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NCBI Description of MLL5
This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcriptional splice variants have been characterized.

Community Annotation of MLL5 Add / Edit MLL5: Annotations

No community annotations yet for MLL5.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MLL5 is highly significantly mutated in
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MLL5 is significantly mutated in
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MLL5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MLL5