MKRN3 Back

makorin, ring finger protein, 3

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NCBI Description of MKRN3
The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MKRN3 is highly significantly mutated in
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MKRN3 is significantly mutated in
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MKRN3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MKRN3