MKRN1 Back

makorin, ring finger protein, 1

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NCBI Description of MKRN1

The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000 [PubMed 10843807]).[supplied by OMIM, Mar 2008].

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MKRN1 is highly significantly mutated in
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MKRN1 is significantly mutated in
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MKRN1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for MKRN1