MGEA5 Back

meningioma expressed antigen 5 (hyaluronidase)

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NCBI Description of MGEA5

The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008].

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


MGEA5 is highly significantly mutated in
MGEA5 is significantly mutated in
MGEA5 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for MGEA5