membrane frizzled-related protein

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NCBI Description of MFRP

This gene encodes a member of the frizzled-related proteins. The encoded protein may play a role in eye development, as mutations in this gene have been associated with nanophthalmos, posterior microphthalmia, retinitis pigmentosa, foveoschisis, and optic disc drusen. The protein is encoded by a bicistronic mRNA, which also encodes C1q and tumor necrosis factor related protein 5.

Community Annotation of MFRP Add / Edit MFRP: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


MFRP is highly significantly mutated in
MFRP is significantly mutated in
MFRP is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for MFRP