MFN1 Back

mitofusin 1

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NCBI Description of MFN1

The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.

Community Annotation of MFN1 Add / Edit MFN1: Annotations

No community annotations yet for MFN1.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


MFN1 is highly significantly mutated in
MFN1 is significantly mutated in
MFN1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for MFN1