MFAP5 Back

microfibrillar associated protein 5

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NCBI Description of MFAP5
This gene encodes a 25-kD microfibril-associated glycoprotein which is rich in serine and threonine residues. It lacks a hydrophobic carboxyl terminus and proline-, glutamine-, and tyrosine-rich regions, which are characteristics of a related 31-kDa microfibril-associated glycoprotein (MFAP2). The close similarity between these two proteins is confined to a central region of 60 aa where precise alignment of 7 cysteine residues occurs. The structural differences suggest that this encoded protein has some functions that are distinct from those of MFAP2.

Community Annotation of MFAP5 Add / Edit MFAP5: Annotations

No community annotations yet for MFAP5.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MFAP5 is highly significantly mutated in
(none)
MFAP5 is significantly mutated in
(none)
MFAP5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MFAP5