MEGF8 Back

multiple EGF-like-domains 8

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NCBI Description of MEGF8
The protein encoded by this gene is a single-pass type I membrane protein of unknown function that contains several EGF-like domains, Kelch repeats, and PSI domains. Defects in this gene are a cause of Carpenter syndrome 2. Two transcript variants encoding different isoforms have been found for this gene.

Community Annotation of MEGF8 Add / Edit MEGF8: Annotations

No community annotations yet for MEGF8.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MEGF8 is highly significantly mutated in
(none)
MEGF8 is significantly mutated in
(none)
MEGF8 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MEGF8