MEF2A Back

myocyte enhancer factor 2A

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of MEF2A
The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.

Community Annotation of MEF2A Add / Edit MEF2A: Annotations

No community annotations yet for MEF2A.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MEF2A is highly significantly mutated in
(none)
MEF2A is significantly mutated in
(none)
MEF2A is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MEF2A