MED8 Back

mediator complex subunit 8

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NCBI Description of MED8
This gene encodes a protein component of the mediator complex, which aids in transcriptional activation through interaction with RNA polymerase II and gene-specific transcription factors. The encoded protein may also function in ubiquitin ligation and protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of MED8 Add / Edit MED8: Annotations

No community annotations yet for MED8.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MED8 is highly significantly mutated in
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MED8 is significantly mutated in
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MED8 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MED8