MED4 Back

mediator complex subunit 4

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NCBI Description of MED4

This gene encodes a component of the Mediator complex. The Mediator complex interacts with DNA-binding gene-specific transcription factors to modulate transcription by RNA polymerase II. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of MED4 Add / Edit MED4: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MED4 is highly significantly mutated in
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MED4 is significantly mutated in
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MED4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for MED4