MED22 Back

mediator complex subunit 22

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NCBI Description of MED22
This gene is located in the surfeit gene cluster, a group of very tightly linked housekeeping genes that do not share sequence similarity. The gene is oriented in a head-to-head fashion with RPL7A (SURF3) and the two genes share a bidirectional promoter. The encoded proteins are localized to the cytoplasm. Two alternative transcript variants encoding different isoforms have been identified for this gene.

Community Annotation of MED22 Add / Edit MED22: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MED22 is highly significantly mutated in
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MED22 is significantly mutated in
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MED22 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MED22