MED21 Back

mediator complex subunit 21

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NCBI Description of MED21

This gene encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants.

Community Annotation of MED21 Add / Edit MED21: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MED21 is highly significantly mutated in
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MED21 is significantly mutated in
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MED21 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for MED21