MED11 Back

mediator complex subunit 11

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of MED11

MED11 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]. Sequence Note: removed 1 base from the 3' end that did not align to the reference genome assembly.

Community Annotation of MED11 Add / Edit MED11: Annotations

No community annotations yet for MED11.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


MED11 is highly significantly mutated in
MED11 is significantly mutated in
MED11 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for MED11