MDM1 Back

Mdm1 nuclear protein homolog (mouse)

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NCBI Description of MDM1
This gene encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of MDM1 Add / Edit MDM1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MDM1 is highly significantly mutated in
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MDM1 is significantly mutated in
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MDM1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MDM1