MCOLN3 Back

mucolipin 3

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NCBI Description of MCOLN3
This gene encodes one of members of the mucolipin cation channel proteins. Mutation studies of the highly similar protein in mice have shown that the protein is found in cochlea hair cells, and mutant mice show early-onset hearing loss and balance problems. Multiple transcript variants encoding different isoforms have been found for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MCOLN3 is highly significantly mutated in
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MCOLN3 is significantly mutated in
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MCOLN3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MCOLN3