MCM9 Back

minichromosome maintenance complex component 9

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NCBI Description of MCM9

The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication. Binding of this protein to chromatin has been shown to be a pre-requisite for recruiting the MCM2-7 helicase to DNA replication origins. This protein also binds, and is a positive regulator of, the chromatin licensing and DNA replication factor 1, CDT1.

Community Annotation of MCM9 Add / Edit MCM9: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


MCM9 is highly significantly mutated in
MCM9 is significantly mutated in
MCM9 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for MCM9