MCM5 Back

minichromosome maintenance complex component 5

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NCBI Description of MCM5
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.

Community Annotation of MCM5 Add / Edit MCM5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MCM5 is highly significantly mutated in
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MCM5 is significantly mutated in
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MCM5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MCM5