MCHR1 Back

melanin-concentrating hormone receptor 1

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NCBI Description of MCHR1
The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MCHR1 is highly significantly mutated in
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MCHR1 is significantly mutated in
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MCHR1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MCHR1