MCAT Back

malonyl CoA:ACP acyltransferase (mitochondrial)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of MCAT

The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Alternative splicing results in multiple transcript variants encoding different isoforms.

Community Annotation of MCAT Add / Edit MCAT: Annotations

No community annotations yet for MCAT.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MCAT is highly significantly mutated in
(none)
MCAT is significantly mutated in
(none)
MCAT is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for MCAT