MC4R Back

melanocortin 4 receptor

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NCBI Description of MC4R
The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity.

Community Annotation of MC4R Add / Edit MC4R: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MC4R is highly significantly mutated in
(none)
MC4R is significantly mutated in
(none)
MC4R is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MC4R