MAT2B Back

methionine adenosyltransferase II, beta

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NCBI Description of MAT2B

The protein encoded by this gene belongs to the methionine adenosyltransferase (MAT) family. MAT catalyzes the biosynthesis of S-adenosylmethionine from methionine and ATP. This protein is the regulatory beta subunit of MAT. Alternative splicing results in multiple transcript variants encoding different isoforms.

Community Annotation of MAT2B Add / Edit MAT2B: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


MAT2B is highly significantly mutated in
MAT2B is significantly mutated in
MAT2B is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for MAT2B