MAS1 Back

MAS1 oncogene

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NCBI Description of MAS1
This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7).

Community Annotation of MAS1 Add / Edit MAS1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MAS1 is highly significantly mutated in
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MAS1 is significantly mutated in
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MAS1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MAS1