MARCKSL1 Back

MARCKS-like 1

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NCBI Description of MARCKSL1
This gene encodes a member of the myristoylated alanine-rich C-kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MARCKSL1 is highly significantly mutated in
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MARCKSL1 is significantly mutated in
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MARCKSL1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MARCKSL1