MARCH10 Back

membrane-associated ring finger (C3HC4) 10

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NCBI Description of MARCH10
MARCH10 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Morokuma et al., 2007 [PubMed 17604280]).[supplied by OMIM, Apr 2010].

Community Annotation of MARCH10 Add / Edit MARCH10: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MARCH10 is highly significantly mutated in
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MARCH10 is significantly mutated in
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MARCH10 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MARCH10