MAPRE2 Back

microtubule-associated protein, RP/EB family, member 2

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NCBI Description of MAPRE2
The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants.

Community Annotation of MAPRE2 Add / Edit MAPRE2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MAPRE2 is highly significantly mutated in
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MAPRE2 is significantly mutated in
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MAPRE2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MAPRE2