MAPK4 Back

mitogen-activated protein kinase 4

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NCBI Description of MAPK4
Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus where it phosphorylates nuclear targets.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MAPK4 is highly significantly mutated in
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MAPK4 is significantly mutated in
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MAPK4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MAPK4