MAP1LC3B Back

microtubule-associated protein 1 light chain 3 beta

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NCBI Description of MAP1LC3B
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.

Community Annotation of MAP1LC3B Add / Edit MAP1LC3B: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MAP1LC3B is highly significantly mutated in
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MAP1LC3B is significantly mutated in
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MAP1LC3B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MAP1LC3B