MAP1LC3A Back

microtubule-associated protein 1 light chain 3 alpha

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of MAP1LC3A
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.

Community Annotation of MAP1LC3A Add / Edit MAP1LC3A: Annotations

No community annotations yet for MAP1LC3A.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MAP1LC3A is highly significantly mutated in
(none)
MAP1LC3A is significantly mutated in
(none)
MAP1LC3A is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MAP1LC3A