MAGI1 Back

membrane associated guanylate kinase, WW and PDZ domain containing 1

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NCBI Description of MAGI1

The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified.

Community Annotation of MAGI1 Add / Edit MAGI1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


MAGI1 is highly significantly mutated in
MAGI1 is significantly mutated in
MAGI1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for MAGI1