MAGEE1 Back

melanoma antigen family E, 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of MAGEE1
This gene encodes an alpha-dystrobrevin-associated MAGE (melanoma-associated antigen) protein, which is a member of the MAGE family. The protein contains a nuclear localization signal in the N-terminus, 30 12-amino acid repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT, and two MAGE domains in the C-terminus. It may play a signaling role in brain, muscle, and peripheral nerve. This gene is located on X chromosome in a region containing loci linked to mental retardation.

Community Annotation of MAGEE1 Add / Edit MAGEE1: Annotations

No community annotations yet for MAGEE1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MAGEE1 is highly significantly mutated in
(none)
MAGEE1 is significantly mutated in
(none)
MAGEE1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MAGEE1