MAGED1 Back

melanoma antigen family D, 1

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NCBI Description of MAGED1
This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.

Community Annotation of MAGED1 Add / Edit MAGED1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MAGED1 is highly significantly mutated in
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MAGED1 is significantly mutated in
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MAGED1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MAGED1