MAGEA2 Back

melanoma antigen family A, 2

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of MAGEA2

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.

Community Annotation of MAGEA2 Add / Edit MAGEA2: Annotations

No community annotations yet for MAGEA2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MAGEA2 is highly significantly mutated in
(none)
MAGEA2 is significantly mutated in
(none)
MAGEA2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for MAGEA2