MAFB Back

v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

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NCBI Description of MAFB
The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns.

Community Annotation of MAFB Add / Edit MAFB: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MAFB is highly significantly mutated in
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MAFB is significantly mutated in
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MAFB is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MAFB