MAD2L2 Back

MAD2 mitotic arrest deficient-like 2 (yeast)

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NCBI Description of MAD2L2
The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins.

Community Annotation of MAD2L2 Add / Edit MAD2L2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MAD2L2 is highly significantly mutated in
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MAD2L2 is significantly mutated in
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MAD2L2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MAD2L2