MAD2L1BP Back

MAD2L1 binding protein

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NCBI Description of MAD2L1BP
The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Community Annotation of MAD2L1BP Add / Edit MAD2L1BP: Annotations

No community annotations yet for MAD2L1BP.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

MAD2L1BP is highly significantly mutated in
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MAD2L1BP is significantly mutated in
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MAD2L1BP is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for MAD2L1BP