MAD2L1 Back

MAD2 mitotic arrest deficient-like 1 (yeast)

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NCBI Description of MAD2L1

MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


MAD2L1 is highly significantly mutated in
MAD2L1 is significantly mutated in
MAD2L1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for MAD2L1