LZTR1 Back

leucine-zipper-like transcription regulator 1

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NCBI Description of LZTR1

This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome.

Community Annotation of LZTR1 Add / Edit LZTR1: Annotations

No community annotations yet for LZTR1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LZTR1 is highly significantly mutated in
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LZTR1 is significantly mutated in
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LZTR1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for LZTR1