lysophospholipase I

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NCBI Description of LYPLA1

Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine in both monomeric and micellar forms. The use of alternate polyadenylation sites has been found for this gene. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet.

Community Annotation of LYPLA1 Add / Edit LYPLA1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


LYPLA1 is highly significantly mutated in
LYPLA1 is significantly mutated in
LYPLA1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for LYPLA1