LY96 Back

lymphocyte antigen 96

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NCBI Description of LY96

This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms.

Community Annotation of LY96 Add / Edit LY96: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LY96 is highly significantly mutated in
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LY96 is significantly mutated in
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LY96 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for LY96