LY6G6D Back

lymphocyte antigen 6 complex, locus G6D

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NCBI Description of LY6G6D

LY6G6D belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Apr 2009].

Community Annotation of LY6G6D Add / Edit LY6G6D: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


LY6G6D is highly significantly mutated in
LY6G6D is significantly mutated in
LY6G6D is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for LY6G6D