LTBR Back

lymphotoxin beta receptor (TNFR superfamily, member 3)

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NCBI Description of LTBR
This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Community Annotation of LTBR Add / Edit LTBR: Annotations

No community annotations yet for LTBR.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LTBR is highly significantly mutated in
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LTBR is significantly mutated in
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LTBR is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for LTBR